A 10-mg nomogram was more effective than a 5-mg nomogram for warfarin induction in outpatient venous thromboembolism.

P a t i e n t s 201 patients who were ≥ 18 years of age (mean age 55 y, 56% men) and had objectively confirmed acute VTE (deep venous thrombosis or pulmonary embolism). Exclusion criteria were a baseline international normalized ratio (INR) > 1.4, platelet count < 50 × 109 cells/mL, need for hospitalization, use of oral anticoagulant therapy in the previous 2 weeks, or high risk for major bleeding. 90-day follow-up was complete.